Skip to main content

Deep thoughts [AKA A little rant]

I was thinking last night (I do that whenever I have trouble sleeping), and I've come to the realization, in the nearly 10 years since my diagnosis with MCL (when I was personally awoken to the issue of cancer), there has been a lot of research done, and too many to fathom clinical trials performed, yet there has been very little [monumental] advancement in the way we deal with and treat cancer.

We've managed to map the entire human genome. We've even come close to discovering the causes of [at least one] cancer, yet there is still no cure, and our approach to treating cancer remains, as it has been for the past 50+ years, to do nothing more than infuse deadly chemicals into the body, in hopes of destroying the cancerous cells. Even one of the biggest advances recently in the treatment of lymphoma, has been the reemergence of Bendamustine, an alkylating agent developed in East Germany in the 1960's.

Yeah, there have been strides made in the use of stem cell transplantation (SCT), and there have even been some new blockbuster drugs that have come on to the market, e.g. Rituxan, Gleevic and Velcade, but they have done little, aside from maybe delaying the inevitable for a few more years, to advance a cure. And even those approaches have their limitations, especially in the case of SCT's, which can produce debilitating side effects, i.e. graft vs host disease (GVHD), that in some cases may be worse than the disease.

You'd just think after all these years, with all the great minds and other resources available in this country, and around the world, there would have been greater strides made towards finding a cure for cancer, or at the very least develop new and safer drugs for the treatment of cancer.

What's even more depressing is with the political upheaval in the US, it appears further advancements related to all types of health issues will be greatly hindered. There are already critical drug shortages showing up around the country, and expected cuts to funding for the National Institute of Health (NIH), portend few [if any] advancements for the foreseeable future.

The principle reason I've delayed treatment so long has been the hope something better would come along, but it seems I'm going to have to wait just a little [a lot] longer.

Comments

Popular posts from this blog

Fatigue! Part II - Maybe it is real?

Or it's actually Motivational Deficiency Disorder, MoDeD (pronounced Mo-Dee-Dee) for short. In a report this week by Roy Moynihan who reports for the British Medical Journal Austrailian scientists may have come across the reason for extreme laziness . The condition is claimed to affect up to one in five Australians and is characterised by overwhelming and debilitating apathy. Neuroscientists at the University of Newcastle in Australia say that in severe cases motivational deficiency disorder can be fatal, because the condition reduces the motivation to breathe. Neurologist Leth Argos is part of the team that has identified the disorder, which can be diagnosed using a combination of positron emission tomography and low scores on a motivation rating scale, previously validated in elite athletes. "This disorder is poorly understood," Professor Argos told the BMJ. "It is underdiagnosed and undertreated." Who knew? Maybe I have MoDeD, from my attempts to become a...

My concerns reaffirmed today

When I was first diagnosed with MCL, I pretty much read just about everything I could get my hands on, I attended various conferences, and I talked to anyone who would listen. One of the most important lessons I learned, and which I've mentioned numerous times before was No one cares more about you than you. But in addition to that, I learned to fear the drug Doxorubicin , AKA Adriamycin, Doxil, Hydroxydoxorubicin, or more affectionately the Red Devil. Besides being a deadly chemical, as is the case with most chemotherapy drugs, it is one of the few chemotherapy drugs known to cause permanent heart damage. I even heard Dr. Sandra Horning , a noted Stanford lymphoma specialist, state at the first lymphoma conference I attended in LA, there was no evidence Doxorubicin provided any added benefit to chemotherapy protocols. This was music to my ears, since Doxorubicin is very common in most lymphoma treatment protocols. And even though Dr. Horning has since changed her tune [which my sk...

Tacitly condoning racism?

I learned something very discouraging in my current events class yesterday, there are a lot more racists and bigots out there then you may think. They may not admit it, or they'll claim otherwise, but when someone says they place the blame for what happened in Charlottesville on both sides, or better yet, they don't know where the blame lays, then they are condoning the action of the white supremacists groups, and in my book that is a racist/bigot. The truth is, there should be no doubt where blame for Charlottesville lays. It lays with the white supremacists, neo-Nazi's, KKK, etc, plain and simple! The hatred, bigotry, and misogyny displayed and espoused by these groups, coupled with the tacit approval of President Trump needs to be confronted at all cost, and history tells us so. If only the Jews, in pre-WWII Germany, had confronted the Nazi's in the same manner, Hitler might never have risen to power, and we would not be looking at the prospect of a  third anti...