Skip to main content

Cancer Treatment! Worse than the disease?

While advances in the treatment of cancer are continuously being made, I have always had an overriding belief that "the cure is worse than the disease". I have just never been able to adequately articulate why I believe that to be so, that is until now. [note]I only wish I had seen this great analogy, on how cancer treatments work, when I was first diagnosed with MCL, and friends and acquaintances would ask why I wasn't starting treatment right away.[/note]

While this person was responding to a promising new technology, CART (Chimeric Antigen Receptor T-cell) therapy, it's still represents an accurate assessment of the current state of all cancer treatment.
I live in the wilderness with many species of wild and domestic animals like Coyotes, Fisher Cats, Fox, Bobcats, Dogs, Cats and yes Bears. Many of these animals help keep a balance of nature and rarely bother humans but sometimes bears can become dangerous, culminating in the rare attack on humans. Let's say a particularly dangerous Bear population begins to breed like wildfire and the threat to me becomes a crisis for which my Atlatl and 12 gage shot gun are no longer able to handle. Along comes a laid off car salesman offering to sell me a brace of T-Rex dinosaurs that he guaranties will eat up the nasty Bear clan. Wow! this is just what I need...... but I don't notice on the contract that I sign and in fine print of course, that although the T-Rexes have proven voracious they are pretty dumb due to small cranial capacity. The guy who trained the T-Rexes to eat my nasty Bears could not get the beasts to recognize just the bad Bears of the nasty Bear clan from the good bears. Training quit at the level where the T-Rexes could recognize and target all four legged fur bearing animals.

The nasty Bear horde threat, being so urgent, I hastily put my money down and let the T-Rexes loose. They clean out the nasty Bears in short order along with the good bears the fox, coyote, bobcat, fisher, domestic cats, dogs and my drunk hirsute neighbor who had been crawling up the path to his cabin one night. Now, losing my garrulous hirsute neighbor was no big loss, I hasten to admit, but soon the environment was overrun by rats and mice who carried the fleas from which I have now contracted bubonic plague. The T-Rexes, having eaten all the animals they could recognize were looking curiously in my direction.

...................

He goes on to explain the challenges in treating cancer which I add here just for some additional insight
The challenge for developing CLL cytotoxic agents, specific to our cancer cells, is that an idiotype (unique to the cancer cell) marker on the surface of the B-cancer cells does not exist or has not been found or cannot yet be exploited for bio-engineering of T-cells or mAbs (monoclonal antibodies like Rituximab/Ofatumumab). The inefficiency of Rituxan/Ofatumumab may prove to be a blessing for those patients who get a good response and who do not react badly, like me, in that some of the good guy B cells are left after therapy and may confer some immune functionality although too many of the bad guys are also left who evolve to resist repeated therapy.

He ends with a statement I find very appropriate
......Live in the moment, and practice gratitude for all that we have. Increasing options abound.

Comments

Linda B said…
Thanks for this. I don't get on my laptop much because of an old shoulder/neck injury, or I would have seen your post sooner. You may remember me from last year - my husband is the Northern CA cyclist you emailed when I first found this site?
I've just come from my oncologist after 1 year of No treatment for MCL diagnosed Feb 2011. He wants to start me on Rituximab and I'm just so fearful of the resultant long-term effects to my body that I haven't done it so far. I have spent this past year on an excellent Vegan diet, rich with fresh organic vegetable and very little fruit or sugar (as best I can). My energy is better, my migraines are fewer and all would be well except that my lymph nodes keeps swelling and now my Spleen is quite enlarged. Sigh...what to do? You give me hope that there is another way.

Popular posts from this blog

My concerns reaffirmed today

When I was first diagnosed with MCL, I pretty much read just about everything I could get my hands on, I attended various conferences, and I talked to anyone who would listen. One of the most important lessons I learned, and which I've mentioned numerous times before was No one cares more about you than you. But in addition to that, I learned to fear the drug Doxorubicin , AKA Adriamycin, Doxil, Hydroxydoxorubicin, or more affectionately the Red Devil. Besides being a deadly chemical, as is the case with most chemotherapy drugs, it is one of the few chemotherapy drugs known to cause permanent heart damage. I even heard Dr. Sandra Horning , a noted Stanford lymphoma specialist, state at the first lymphoma conference I attended in LA, there was no evidence Doxorubicin provided any added benefit to chemotherapy protocols. This was music to my ears, since Doxorubicin is very common in most lymphoma treatment protocols. And even though Dr. Horning has since changed her tune [which my sk...

Bowling: A metaphor on life [sorta]

Over the past 15+ years the game of bowling has changed dramatically. Not only has the equipment changed, making it easier for bowlers of all ages and physical conditions to participate, and score well, but there have even been major advances to how the lanes are prepared for the start of bowling. No longer is it just heavy oil, light oil, long oil, short oil, or no oil, with the latest equipment, the amount of oil can be varied from front to back and side to side, producing a myriad of patterns designed to make the game more interesting, more challenging and as you might surmise, more frustrating. No longer does the "one ball fits all" approach work any more either. In order to navigate all the differing possible lane conditions, you need to have a varied selection of bowling balls. Most pros will tell you the average bowler needs 3 balls, plus a ball for spares, but to be an above average bowler you'll need at least 6 balls, with many possessing more than that. But just...

Fatigue! Part II - Maybe it is real?

Or it's actually Motivational Deficiency Disorder, MoDeD (pronounced Mo-Dee-Dee) for short. In a report this week by Roy Moynihan who reports for the British Medical Journal Austrailian scientists may have come across the reason for extreme laziness . The condition is claimed to affect up to one in five Australians and is characterised by overwhelming and debilitating apathy. Neuroscientists at the University of Newcastle in Australia say that in severe cases motivational deficiency disorder can be fatal, because the condition reduces the motivation to breathe. Neurologist Leth Argos is part of the team that has identified the disorder, which can be diagnosed using a combination of positron emission tomography and low scores on a motivation rating scale, previously validated in elite athletes. "This disorder is poorly understood," Professor Argos told the BMJ. "It is underdiagnosed and undertreated." Who knew? Maybe I have MoDeD, from my attempts to become a...